Article
Dietary fat clearance in normal subjects is modulated by genetic variation at the apolipoprotein B gene locus.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1997
Lopez-Miranda J, Ordovas J M, Ostos M A, Marin C, Jansen S, Salas J, Blanco-Molina A, Jimenez-Pereperez J A, Lopez-Segura F, Perez-Jimenez F
Abstract excerpt
Apolipoprotein B (apo B) plays a dominant role in cholesterol homeostasis. Several polymorphic sites within or adjacent to the gene locus for apo B have been detected. The X+ allele (XbaI restriction site present) of the XbaI restriction fragment polymorphism on the apo B gene has been found in some studies to be associated with higher serum cholesterol and/or triglyceride levels and with greater dietary...
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