Article
Acute disseminated encephalomyelitis: clinical features, HLA DRB1*1501, HLA DRB1*1503, HLA DQA1*0102, HLA DQB1*0602, and HLA DPA1*0301 allelic association study.
Arquivos de neuro-psiquiatria - 1 Sept 2009
Alves-Leon Soniza Vieira, Veluttini-Pimentel Maria Lucia, Gouveia Maria Emmerick, Malfetano Fabíola Rachid, Gaspareto Emerson L, Alvarenga Marcos P, Frugulhetti Izabel, Quirico-Santos Thereza
Abstract excerpt
We evaluated the frequency, demographic, clinical, disability evolution and genetic association of HLA DRB1*1501, DRB1*1503, DQA1*0102, DQB1*0602 and DPA1*0301 alleles in patients diagnosed as acute disseminated encephalomyelitis (ADEM) among a population of CNS demyelinating diseases. Fifteen patients (8.4%) of our series were diagnosed as ADEM. The mean age onset was 35.23 years (range 12 to 77), 53.3% were...
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