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High-Level Rifampin Resistance Correlates with Multiple Mutations in the<i>rpoB</i>Gene of Pulmonary Tuberculosis Isolates from the Afghanistan Border of Iran

31 Aug 2009

Abstract excerpt

The aim of this study was to investigate the significance of multiple mutations in the rpoB gene as well as predominant nucleotide changes and their correlation with high levels of resistance to rifampin (rifampicin) in Mycobacterium tuberculosis isolates that were randomly collected from the sputa of 46 patients with primary and secondary cases of active pulmonary tuberculosis from the southern region...

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PMID: 19721079
DOI: 10.1128/jcm.r00548-09

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