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Article

VEGF-D deficiency in mice does not affect embryonic or postnatal lymphangiogenesis but reduces lymphatic metastasis.

The Journal of pathology - 1 Nov 2009

Koch Marta, Dettori Daniela, Van Nuffelen An, Souffreau Joris, Marconcini Lucia, Wallays Goedele, Moons Lieve, Bruyère Françoise, Oliviero Salvatore, Noel Agnes, Foidart Jean-Michel, Carmeliet Peter, Dewerchin Mieke

Abstract excerpt

Vascular endothelial growth factor-D (VEGF-D) is one of the two ligands of the VEGFR-3 receptor on lymphatic endothelial cells. Gene-silencing studies in mice and Xenopus tadpoles recently showed that the role of endogenous VEGF-D in lymphatic development is moderate. By contrast, exogenous VEGF-...

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PMID: 19718705
DOI: 10.1002/path.2605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19718705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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