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Article

Gonadal malignancy risk and prophylactic gonadectomy in disorders of sexual development

1 Jan 2015

Abstract excerpt

Disorders of sex development (DSD) are a generic definition including any problem noted at birth where the genitalia are atypical in relation to the chromosomes or gonads. The most important clinical problems in DSD comprise physical and psychological disturbances and the risk of gonadal tumor development. Germ cell tumor risk is lowest (<5%) in patients with defects in androgene action or synthesis (such as...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sexual Differentiation and Disorders
Share to Urological Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25879315
DOI: 10.1515/jpem-2014-0522

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