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Article

Human Y chromosome base-substitution mutation rate measured by direct sequencing in a deep-rooting pedigree.

Current biology : CB - 15 Sept 2009

Xue Yali, Wang Qiuju, Long Quan, Ng Bee Ling, Swerdlow Harold, Burton John, Skuce Carl, Taylor Ruth, Abdellah Zahra, Zhao Yali, MacArthur Daniel G, Quail Michael A, Carter Nigel P, Yang Huanming, Tyler-Smith Chris

Abstract excerpt

Understanding the key process of human mutation is important for many aspects of medical genetics and human evolution. In the past, estimates of mutation rates have generally been inferred from phenotypic observations or comparisons of homologous sequences among closely related species. Here, we apply new sequencing technology to measure directly one mutation rate, that of base substitutions on the human Y...

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Share to Chromosomes, Human, Y
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Point Mutation

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 19716302
DOI: 10.1016/j.cub.2009.07.032
PMCID: PMC2748900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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