Article
Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.
The Biochemical journal - 15 May 1990
Steinkasserer A, Weiss E H, Schwaeble W, Linke R P
Abstract excerpt
Serum amyloid A (SAA), a chemically polymorphic protein, is the most sensitive marker protein of the acute phase and the precursor of reactive amyloidosis, which is characterized by deposits of amyloid A protein (AA). We investigated the variability of the SAA gene family in one individual by sequencing 11 SAA-specific clones from an acute-phase-liver cDNA library. At least five different SAA variants were...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA
- DNA Probes
- DNA Restriction Enzymes
- Deoxyribonucleases, Type II Site-Specific
- Genetic Variation
- Humans
- Liver
- Molecular Sequence Data
- Nucleic Acid Hybridization
