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Article

Effect of amino acid variations in the central region of human serum amyloid A on the amyloidogenic properties.

Biochemical and biophysical research communications - 31 Jan 2014

Takase Hiroka, Tanaka Masafumi, Miyagawa Sachiko, Yamada Toshiyuki, Mukai Takahiro

Abstract excerpt

Human serum amyloid A (SAA) is a precursor protein of the amyloid fibrils that are responsible for AA amyloidosis. Of the four human SAA genotypes, SAA1 is most commonly associated with AA amyloidosis. Furthermore, SAA1 has three major isoforms (SAA1.1, 1.3, and 1.5) that differ by single amino acid variations at two sites in their 104-amino acid sequences. In the present study, we examined the effect of amino...

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Source

Identifiers

PMID: 24440699
DOI: 10.1016/j.bbrc.2014.01.029

Genes

SAA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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