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Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients

27 Aug 2009

Abstract excerpt

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a lethal disorder characterized by progressive degeneration of motor neurons in the brain and spinal cord. Diagnosis is mainly based on clinical symptoms, and there is currently no therapy to stop the disease or slow its progression. Since access to spinal cord tissue is not possible at disease onset, we investigated changes in gene expression profiles in whole...

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PMID: 19712483
DOI: 10.1186/1471-2164-10-405

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