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Article

Genetic variability of RyR2 and CASQ2 genes in an Asian population.

Forensic science international - 20 Nov 2009

Wong Chang Hua, Koo Seok Hwee, She George Qiongze, Chui Paul, Lee Edmund Jon Deoon

Abstract excerpt

We analyzed the coding regions of the cardiac calcium-handling genes, ryanodine receptor 2 (RyR2) and calsequestrin 2 (CASQ2) for genetic variants in a healthy Chinese population (n=95) and in a cohort of 28 sudden unexplained death victims. Mutations in RyR2 and CASQ2 have been shown to alter calcium homeostasis during excitation-contraction coupling and predispose individuals to fatal cardiac arrhythmias. The...

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Source

Identifiers

PMID: 19709828
DOI: 10.1016/j.forsciint.2009.07.019

Genes

CASQ2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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