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Article

Single-feature polymorphism discovery by computing probe affinity shape powers.

BMC genetics - 26 Aug 2009

Xu Wayne Wenzhong, Cho Seungho, Yang S Samuel, Bolon Yung-Tsi, Bilgic Hatice, Jia Haiyan, Xiong Yanwen, Muehlbauer Gary J

Abstract excerpt

BACKGROUND: Single-feature polymorphism (SFP) discovery is a rapid and cost-effective approach to identify DNA polymorphisms. However, high false positive rates and/or low sensitivity are prevalent in previously described SFP detection methods. This work presents a new computing method for SFP discovery. RESULTS: The probe affinity differences and affinity shape powers formed by the neighboring probes in each...

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Identifiers

PMID: 19709416
DOI: 10.1186/1471-2156-10-48
PMCID: PMC2746803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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