Article
Detecting single-feature polymorphisms using oligonucleotide arrays and robustified projection pursuit.
Bioinformatics (Oxford, England) - 15 Oct 2005
Cui Xinping, Xu Jin, Asghar Rehana, Condamine Pascal, Svensson Jan T, Wanamaker Steve, Stein Nils, Roose Mikeal, Close Timothy J
Abstract excerpt
MOTIVATION: Genomic DNA was hybridized to oligonucleotide microarrays to identify single-feature polymorphisms (SFP) for Arabidopsis, which has a genome size of approximately 130 Mb. However, that method does not work well for organisms such as barley, with a much larger 5200 Mb genome. In the present study, we demonstrate SFP detection using a small number of replicate datasets and complex RNA as a surrogate for...
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