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Article

The Regulation of Type I Interferon Production by Paramyxoviruses

24 Aug 2009

Abstract excerpt

Experimentally, paramyxoviruses are conventionally considered good inducers of type I interferons (IFN-alpha/beta), and have been used as agents in the commercial production of human IFN-alpha. However, in the last few years it has become clear that viruses in general mount a major challenge to the IFN system, and paramyxoviruses are no exception. Indeed, most paramyxoviruses encode mechanisms to inhibit both the...

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PMID: 19702509
DOI: 10.1089/jir.2009.0071

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