Molecular milestones that signal axonal maturation and the commitment of human spinal cord precursor cells to the neuronal or glial phenotype in development.

Abstract excerpt

Insights into the programmatic induction of neuronal and glial genes during human embryogenesis have depended largely on extrapolations of data derived from experimental mammals. However, the assumptions upon which these extrapolations are based have not been rigorously tested. Indeed, practically no information is available even on the human counterparts of the relatively small subset of well-characterized,...

Topics

• Animals
• Axons
• Embryo, Mammalian
• Female
• Fetus
• Gestational Age
• Hominidae
• Humans
• Immunohistochemistry
• Infant, Newborn
• Intermediate Filament Proteins