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Article

The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila.

Proceedings. Biological sciences - 7 Nov 2009

Ikeya Tomoatsu, Broughton Susan, Alic Nazif, Grandison Richard, Partridge Linda

Abstract excerpt

Insulin/IGF-like signalling (IIS) is an evolutionarily conserved pathway that has diverse functions in multi-cellular organisms. Mutations that reduce IIS can have pleiotropic effects on growth, development, metabolic homeostasis, fecundity, stress resistance and lifespan. IIS is also modified by extrinsic factors. For instance, in the fruitfly Drosophila melanogaster, both nutrition and stress can alter the...

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Identifiers

PMID: 19692410
DOI: 10.1098/rspb.2009.0778
PMCID: PMC2817276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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