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Article

Molecular basis of five apolipoprotein B gene polymorphisms in noncoding regions.

Journal of lipid research - 1 Jan 1990

Huang L S, Ripps M E, Breslow J L

Abstract excerpt

Restriction fragment length polymorphisms (RFLPs) are useful in linkage and clinical association studies of human diseases. In this report, we characterize the molecular basis and frequencies of two new RFLPs, AvaII and BalI, two previously reported RFLPs, HincII and PvuII, and one new sequence polymorphism in the human apolipoprotein B gene. For the AvaII RFLP, the two alleles yield either a 1 kb fragment or 0.7...

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PMID: 1968951

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