Article
High-throughput mouse phenomics for characterizing mammalian gene function.
Nature reviews. Genetics - 1 Jun 2018
Brown Steve D M, Holmes Chris C, Mallon Ann-Marie, Meehan Terrence F, Smedley Damian, Wells Sara
Abstract excerpt
We are entering a new era of mouse phenomics, driven by large-scale and economical generation of mouse mutants coupled with increasingly sophisticated and comprehensive phenotyping. These studies are generating large, multidimensional gene-phenotype data sets, which are shedding new light on the mammalian genome landscape and revealing many hitherto unknown features of mammalian gene function. Moreover, these...
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