Article
Olfactory impairment in presymptomatic Alzheimer's disease.
Annals of the New York Academy of Sciences - 1 Jul 2009
Wilson Robert S, Arnold Steven E, Schneider Julie A, Boyle Patricia A, Buchman Aron S, Bennett David A
Abstract excerpt
Alzheimer's disease (AD) impairs olfaction, but it is uncertain how early this occurs in the disease process and whether the effect can be accounted for by other behavioral or genetic markers of the disease. We administered the Brief Smell Identification Test (BSIT) to 471 older people without dementia or cognitive impairment who then completed annual clinical evaluations and brain autopsy at death. BSIT score...
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