Article
Olfactory discrimination predicts cognitive decline among community-dwelling older adults.
Translational psychiatry - 22 May 2012
Sohrabi H R, Bates K A, Weinborn M G, Johnston A N B, Bahramian A, Taddei K, Laws S M, Rodrigues M, Morici M, Howard M, Martins G, Mackay-Sim A, Gandy S E, Martins R N
Abstract excerpt
The presence of olfactory dysfunction in individuals at higher risk of Alzheimer's disease has significant diagnostic and screening implications for preventive and ameliorative drug trials. Olfactory threshold, discrimination and identification can be reliably recorded in the early stages of neurodegenerative diseases. The current study has examined the ability of various olfactory functions in predicting...
Topics
- Aged
- Aged, 80 and over
- Agnosia
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Cohort Studies
- Discrimination, Psychological
- Disease Progression
- Female