Article
Very early changes in olfactory functioning due to Alzheimer's disease and the role of apolipoprotein E in olfaction.
Annals of the New York Academy of Sciences - 30 Nov 1998
Bacon A W, Bondi M W, Salmon D P, Murphy C
Abstract excerpt
Alzheimer's disease (AD) is a progressive neurodegenerative illness marked by memory loss and at least one other cognitive disturbance. Early diagnosis of the disease has proved difficult and has therefore been the focus of much research. Apolipoprotein E (ApoE), a protein manufactured and distributed throughout the body, has shown specificity of binding to the beta A4 peptide, the primary component in the senile...
Topics
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Humans
- Smell