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Differential effects of short-chain fatty acids and iron on expression of iha in Shiga-toxigenic Escherichia coli

30 Oct 2009

Abstract excerpt

Shiga-toxigenic Escherichia coli (STEC) colonizing the bowel are exposed to a variety of short-chain fatty acids (SCFAs), including acetate, propionate and butyrate, produced by gut microflora. However, the total concentrations and relative amounts of SCFAs in the lumen vary with intestinal niche. Here we report that conditions simulating SCFA concentrations present in the human gut trigger expression of the iha...

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PMID: 19684070
DOI: 10.1099/mic.0.029454-0

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