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Article

Marker haplotype association with growth in German cystic fibrosis patients.

Human genetics - 1 Feb 1990

Tümmler B, Aschendorff A, Darnedde T, Fryburg K, Maass G, Hundrieser J

Abstract excerpt

In 84 families with 101 children with cystic fibrosis (CF) and 103 unaffected siblings, the haplotype of CF chromosomes was determined with six restriction fragment length polymorphism (RFLP) markers that span the CF gene locus. Patient groups with different genotypes in the more distant flanking marker loci MET D, MET H, and D7S8 differed significantly from each other with respect to percentile height and...

Topics

Adolescent
Adult
Age Factors
Alleles
Body Height
Body Weight
Child
Child, Preschool
Cystic Fibrosis
Female
Genetic Markers
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Infant

Male

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1968035
DOI: 10.1007/BF00200573

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1968035-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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