Article
Allele frequencies of cystic fibrosis-linked markers and F508 deletion in affected Hungarian families.
Acta paediatrica Hungarica - 1 Jan 1992
Endreffy E, Burg K, Gyurkovits K, Kálmán M, László A, Raskó I
Abstract excerpt
Linked marker haplotype analysis of 16 cystic fibrosis (CF)-affected children, 3 fetuses, 1 healthy child and their parents was performed by restriction fragment length polymorphism (RFLP) for J3.11, Met H, Met D, XV-2c, KM.19 markers. Polymerase chain reaction (PCR) to detect the main mutation o...
Topics
- Adult
- Alleles
- Child
- Chorionic Villi Sampling
- Cystic Fibrosis
- Female
- Gene Deletion
- Genetic Linkage
- Genetic Markers
- Humans
- Male
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Pregnancy