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Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways

10 Aug 2009

Abstract excerpt

Activation of hepatic stellate cells (HSCs), which is regulated by multiple signal transduction pathways, is the key event in liver fibrosis. Moreover, members of these pathways are important targets for microRNAs (miRNAs). To better understand the critical pathways of HSC activation, we performed comprehensive comparative bioinformatics analysis of microarrays of quiescent and activated HSCs. Changes in miRNAs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19674103
DOI: 10.1111/j.1742-4658.2009.07213.x

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