HLA-B8, DR3: a new risk factor for graft failure after renal transplantation in patients with underlying immunoglobulin A nephropathy.

doi:10.1111/j.1399-0012.2009.01059.x

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Article

HLA-B8, DR3: a new risk factor for graft failure after renal transplantation in patients with underlying immunoglobulin A nephropathy.

Clinical transplantation - 1 Jan 2000

Andresdottir Margret B, Haasnoot Geert W, Persijn Guido G, Claas Frans H J

Abstract excerpt

BACKGROUND: The HLA-B8, DR3 haplotype has been associated with high immune reactivity. In this study, we have tested whether this haplotype has differential effect on graft survival in patients with IgAN compared with control patients. METHODS: From the Eurotransplant Registry we analyzed graft survival of 1207 recipients with IgAN and 7935 control patients with non-glomerular diseases. Death-censored graft loss...

Topics

Female
Genotype
Glomerulonephritis, IGA
Graft Rejection
HLA-B8 Antigen
Haplotypes
Humans
Kidney Transplantation
Male
Middle Aged
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

Receptors, Tumor Necrosis Factor, Member 25

Registries

Risk Factors

Survival Rate

Treatment Outcome

Source

Open in PubMed

Identifiers

PMID: 19674013
DOI: 10.1111/j.1399-0012.2009.01059.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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