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Article

Restless legs syndrome, rapid eye movement sleep behavior disorder, and hypersomnia in patients with two parkin mutations.

Movement disorders : official journal of the Movement Disorder Society - 15 Oct 2009

Limousin Nadège, Konofal Eric, Karroum Elias, Lohmann Ebba, Theodorou Ioannis, Dürr Alexandra, Arnulf Isabelle

Abstract excerpt

Parkin gene mutations cause a juvenile parkinsonism. Patients with these mutations may commonly exhibit REM sleep behaviour disorders, but other sleep problems (insomnia, sleepiness, restless legs syndrome) have not been studied. The aim of this study was to evaluate the sleep-wake phenotype in patients with two parkin mutations, compared with patients with idiopathic Parkinson's disease (iPD). Sleep interview...

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PMID: 19672985
DOI: 10.1002/mds.22711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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