Article
Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations.
Annals of neurology - 1 Oct 2004
Kumru Hatice, Santamaria Joan, Tolosa Eduardo, Valldeoriola Francesc, Muñoz Esteban, Marti Maria J, Iranzo Alex
Abstract excerpt
Rapid eye movement sleep behavior disorder (RBD) in the setting of parkinsonism or dementia often reflects an underlying synucleinopathy. Lewy bodies, intraneuronal aggregates containing abnormal alpha-synuclein, are absent in most cases of parkinsonism with parkin mutations (Park2). We performed clinical history and video-polysomnography in 10 Park2 patients (seven men; age, 51.2 +/- 11.6 years; parkinsonism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
