Article
Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism.
Journal of proteomics - 2 Nov 2009
Núñez Vitelbina, Cid Pedro, Sanz Libia, De La Torre Pilar, Angulo Yamileth, Lomonte Bruno, Gutiérrez José María, Calvete Juan J
Abstract excerpt
The venom proteomes of Bothrops atrox from Colombia, Brazil, Ecuador, and Perú were characterized using venomic and antivenomic strategies. Our results evidence the existence of two geographically differentiated venom phenotypes. The venom from Colombia comprises at least 26 different proteins belonging to 9 different groups of toxins. PI-metalloproteinases and K49-PLA(2) molecules represent the most abundant...
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