Top-down proteomics of venoms from five Micrurus species from Costa Rica: Comparative composition of phospholipase A2-rich vs three-finger toxin-rich phenotypes.

Abstract excerpt

Coralsnakes of the genus Micrurus include more than 80 species distributed in the American continent. They produce potent neurotoxic venoms acting at the neuromuscular junction and potentially leading to respiratory paralysis and death. The vast majority of proteins in coralsnake venoms belong to the three-finger toxin (3FTx) and the group I phospholipase A2 (PLA2) families. Previous studies using 'bottom-up'...

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