Article
Phenotypic dichotomy in Crotalus durissus ruruima venom and potential consequences for clinical management of snakebite envenomations.
PLoS neglected tropical diseases - 1 Aug 2025
Colombini Mônica, Rocha Anderson M, Freitas-de-Sousa Luciana A, Chaves Alison F A, Serrano Solange M T, Souza Vinicius C, Viala Vincent L, Junqueira-Azevedo Inácio L M, Cerni Felipe A, Sartim Marco A, Sachett Jacqueline A G, Monteiro Wuelton M, Grazziotin Felipe G, Wen Fan Hui, Pucca Manuela B, Moura-da-Silva Ana M
Abstract excerpt
BACKGROUND: Phenotypic polymorphism in rattlesnake venoms is well-documented, with a dichotomy between hemorrhagic (Type I) and neurotoxic (Type II) venoms. In South America, the Type II phenotype is predominant; however, evidence of Type I venom in Crotalus durissus ruruima raises concerns about the efficacy of the Crotalus antivenom, which is prepared only with Type II venoms. Consequently, the...
Read the complete abstract on PubMedTopics
- Animals
- Crotalus
- Crotalid Venoms
- Snake Bites
- Antivenins