Article
Snake Venomics of the Arboreal Talamancan Palm-Pitviper, Bothriechis nubestris, Provides Clues on the Origin of a Phenotypic Dichotomy between Type-I and Type-II Venoms.
Journal of proteome research - 6 Jun 2025
Chacón Johelen, Chaves-Araya Stephanie, Mena Gianni, Chang-Castillo Arturo, Díaz Cecilia, Bonilla Fabián, Sasa Mahmood, Calvete Juan J, Sanz Libia, Gutiérrez José María, Lomonte Bruno, Fernández Julián
Abstract excerpt
We report the biochemical and proteomic characterization of the venom of the arboreal Talamancan palm-pitviper, Bothriechis nubestris, a species endemic to north and central parts of the Costa Rican Cordillera de Talamanca, at 2100 to 3000 m above sea level. The Talamancan palm-pitviper venom arsenal comprised the translated products of 26 unique transcripts into 10 toxin classes, where metalloproteinases PIIa...
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