Article
MHC2TA rs4774C and HHV-6A active replication in multiple sclerosis patients.
European journal of neurology - 1 Jan 2010
Alvarez-Lafuente R, Martinez A, Garcia-Montojo M, Mas A, De Las Heras V, Dominguez-Mozo M I, Maria Del Carmen C, López-Cavanillas M, Bartolome M, Gomez de la Concha E, Urcelay E, Arroyo R
Abstract excerpt
BACKGROUND AND PURPOSE: In a previous report, a strong gene-environment interaction between human herpesvirus 6A (HHV6A) active replication and MHC2TA rs4774C was demonstrated. The objectives of this study were: (i) to reappraise the association that was found in the previous study; (ii) to evaluate if MS patients with minor allele C and HHV-6A active infection had different clinical behavior; and (iii) to...
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