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Biomineralization in Humans: Making the Hard Choices in Life

17 Nov 2009

Abstract excerpt

The skeleton, teeth, and otoconia are normally the only mineralized tissues or organs in the human body. We describe physiological biomineralization in collagenous matrices as well as a more derived noncollagenous matrix. The origin of the collagenous matrices used in mineralized skeletal tissues can be traced to a soft tissue in early Metazoa. In early vertebrates, a genetic system coding for ancient soft...

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PMID: 19659443
DOI: 10.1146/annurev-genet-102108-134242

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