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Article

Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects.

Metabolic syndrome and related disorders - 1 Dec 2009

Tanyolaç Sinan, Bremer Andrew A, Hodoglugil Uğur, Movsesyan Irina, Pullinger Clive R, Heiner Steven W, Malloy Mary J, Kane John P, Goldfine Ira D

Abstract excerpt

BACKGROUND: Hypertriglyceridemia is associated with insulin resistance, type 2 diabetes, and the metabolic syndrome. Membrane glycoprotein PC-1 (also termed ENPP1) is a direct insulin receptor inhibitor, and certain polymorphisms of the ENPP1/PC-1 gene have been associated with insulin resistance, type 2 diabetes, obesity, and diabetic complications. METHODS: We examined the effect of 3 ENPP1/PC-1 variants...

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Identifiers

PMID: 19656007
DOI: 10.1089/met.2009.0027
PMCID: PMC3139525

Genes

ENPP1

Variants

rs1044498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects.PMID 19656007Read ↗

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