Article
Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone
4 Aug 2009
Abstract excerpt
Current therapies for glioblastoma (GBM) target bulk tumor through measures such as resection and radiotherapy. However, recent evidence suggests that targeting a subset of tumor cells, so-called cancer stem cells, may be critical for inhibiting tumor growth and relapse. The subventricular zone (SVZ), which lines the ventricles of the brain, is thought to be the origin for the majority of neural stem cells and...
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