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Article

Asthma and pregnancy: emerging evidence of epigenetic interactions in utero

18 Aug 2009

Abstract excerpt

PURPOSE OF REVIEW: Pregnancy is arguably the most critical period of developmental programming. Here, we particularly focus on the emerging paradigm that disease propensity is epigenetically determined by maternal exposures that have the capacity to activate or silence fetal genes through alterations in DNA and histone methylation, histone acetylation, and chromatin structure. RECENT FINDINGS: The most notable...

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PMID: 19652594
DOI: 10.1097/aci.0b013e328330634f

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