Article
Nicotine can skew the characterization of the macrophage type-1 (MPhi1) phenotype differentiated with granulocyte-macrophage colony-stimulating factor to the MPhi2 phenotype.
Biochemical and biophysical research communications - 9 Oct 2009
Yanagita Manabu, Kobayashi Ryohei, Murakami Shinya
Abstract excerpt
Macrophages (MPhis) exhibit functional heterogeneity and plasticity in the local microenvironment. Recently, it was reported that MPhis can be divided into proinflammatory MPhis (MPhi1) and anti-inflammatory MPhis (MPhi2) based on their polarized functional properties. Here, we report that nicoti...
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