Article
Characterization of LMX-1A as a metastasis suppressor in cervical cancer.
The Journal of pathology - 1 Oct 2009
Liu Chin-Yu, Chao Tai-Kuang, Su Po-Hsuan, Lee Hsin-Yi, Shih Yu-Lueng, Su Her-Young, Chu Tang-Yuan, Yu Mu-Hsien, Lin Ya-Wen, Lai Hung-Cheng
Abstract excerpt
DNA methylation is important in cancer development and is a promising biomarker for cancer detection. An epigenomic approach used in our previous work showed that LMX-1A is methylation-silenced in cervical cancer. LMX-1A, a LIM-homeobox gene, is known to participate in developmental events; however, there are at present no data on the role of LMX-1A in cancers. In this study, we characterized the function of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
