Article
Calcium is essential for the major pseudopilin in the type 2 secretion system.
The Journal of biological chemistry - 18 Sept 2009
Korotkov Konstantin V, Gray Miranda D, Kreger Allison, Turley Stewart, Sandkvist Maria, Hol Wim G J
Abstract excerpt
The pseudopilus is a key feature of the type 2 secretion system (T2SS) and is made up of multiple pseudopilins that are similar in fold to the type 4 pilins. However, pilins have disulfide bridges, whereas the major pseudopilins of T2SS do not. A key question is therefore how the pseudopilins, and in particular, the most abundant major pseudopilin, GspG, obtain sufficient stability to perform their function....
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