Article
Increased variation in ADH enzyme activity in Drosophila mutation-accumulation experiment is not due to transposable elements at the Adh structural gene.
Genetics - 1 Dec 1990
Aquadro C F, Tachida H, Langley C H, Harada K, Mukai T
Abstract excerpt
We present here a molecular analysis of the region surrounding the structural gene encoding alcohol dehydrogenase (Adh) in 47 lines of Drosophila melanogaster that have each accumulated mutations for 300 generations. While these lines show a significant increase in variation of alcohol dehydrogenase enzyme activity compared to control lines, we found no restriction map variation in a 13-kb region including the...
Topics
- Alcohol Dehydrogenase
- Analysis of Variance
- Animals
- DNA Transposable Elements
- Drosophila melanogaster
- Genes
- Genetic Variation
- Mutation
- Restriction Mapping