Article
Associations between DNA sequence variation and variation in expression of the Adh gene in natural populations of Drosophila melanogaster.
Genetics - 1 Oct 1991
Laurie C C, Bridgham J T, Choudhary M
Abstract excerpt
A large part of the genetic variation in alcohol dehydrogenase (ADH) activity level in natural populations of Drosophila melanogaster is associated with segregation of an amino acid replacement polymorphism at nucleotide 1490, which generates a difference in electrophoretic mobility. Part of the...
Topics
- Alcohol Dehydrogenase
- Amino Acid Sequence
- Animals
- Base Sequence
- Cross Reactions
- DNA
- DNA Transposable Elements
- Drosophila melanogaster
- Gene Expression Regulation
- Genetic Variation
- Linkage Disequilibrium
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Polymorphism, Restriction Fragment Length
- Restriction Mapping
- Sequence Alignment
- Transformation, Genetic