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Article

Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits.

Behavioral neuroscience - 1 Aug 2009

Ward Ryan D, Kellendonk Christoph, Simpson Eleanor H, Lipatova Olga, Drew Michael R, Fairhurst Stephen, Kandel Eric R, Balsam Peter D

Abstract excerpt

Increased striatal dopamine D2 receptor activity is thought to contribute to the pathophysiology of schizophrenia. To model this condition in mice, Kellendonk et al. (2006) generated transgenic mice that selectively overexpress the D2 receptor in striatum (D2OE). Drew et al. (2007) reported that...

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Identifiers

PMID: 19634929
DOI: 10.1037/a0016503
PMCID: PMC2791672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19634929-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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