Article
Haplotype-based case-control study between human apurinic/apyrimidinic endonuclease 1/redox effector factor-1 gene and cerebral infarction.
Clinical biochemistry - 1 Oct 2009
Naganuma Takahiro, Nakayama Tomohiro, Sato Naoyuki, Fu Zhenyan, Yamaguchi Mai, Soma Masayoshi, Aoi Noriko, Usami Ron, Doba Nobutaka, Hinohara Shigeaki
Abstract excerpt
OBJECTIVES: The aim of this study was to investigate the relationship between cerebral infarction (CI) and the human apurinic/apyrimidinic endonuclease 1/redox effector factor-1 (APE1/REF-1) gene using single-nucleotide polymorphisms (SNPs) and a haplotype-based case-control study. DESIGN AND METHODS: We selected 5 SNPs in the human APE1/REF1 gene (rs1760944, rs3136814, rs17111967, rs3136817 and rs1130409), and...
