Article
A prospective study of polymorphisms of DNA repair genes XRCC1, XPD23 and APE/ref-1 and risk of stroke in Linxian, China.
Journal of epidemiology and community health - 1 Aug 2007
Mahabir Somdat, Abnet Christian C, Qiao You-Lin, Ratnasinghe Luke D, Dawsey Sanford M, Dong Zhi-Wei, Taylor Philip R, Mark Steven D
Abstract excerpt
BACKGROUND: Stroke is the leading cause of death in Linxian, China. Although there is evidence of DNA damage in experimental stroke, no data exist on DNA repair and stroke in human populations. AIM: To assess the risk of stroke conferred by polymorphisms in the DNA repair genes, XRCC1, XPD23 and APE/ref-1 in a cohort of individuals originally assembled as subjects in two cancer prevention trials in Linxian,...
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