Article
Association of extracellular superoxide dismutase gene with cerebral infarction in women: a haplotype-based case-control study.
Hereditas - 1 Dec 2008
Naganuma Takahiro, Nakayama Tomohiro, Sato Naoyuki, Fu Zhenyan, Soma Masayoshi, Aoi Noriko, Hinohara Shigeaki, Doba Nobutaka, Usami Ron
Abstract excerpt
It has been reported that oxidative stress is a factor in cerebral infarction (CI). Extracellular superoxide dismutase (EC-SOD) is important in preventing oxidative stress, and the cerebral infarct size of EC-SOD knockout mice is significantly larger than that in wild-type controls. The aim of this study was to investigate the relationship between CI and the human EC-SOD gene using single-nucleotide polymorphism...
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