Article
GMP-based CD133(+) cells isolation maintains progenitor angiogenic properties and enhances standardization in cardiovascular cell therapy.
Journal of cellular and molecular medicine - 1 Jun 2010
Gaipa Giuseppe, Tilenni Manuela, Straino Stefania, Burba Ilaria, Zaccagnini Germana, Belotti Daniela, Biagi Ettore, Valentini Marco, Perseghin Paolo, Parma Matteo, Campli Cristiana Di, Biondi Andrea, Capogrossi Maurizio C, Pompilio Giulio, Pesce Maurizio
Abstract excerpt
The aim of the present study was to develop and validate a good manufacturing practice (GMP) compliant procedure for the preparation of bone marrow (BM) derived CD133(+) cells for cardiovascular repair. Starting from available laboratory protocols to purify CD133(+) cells from human cord blood, w...
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