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Article

Sod2 overexpression preserves myoblast mitochondrial mass and function, but not muscle mass with aging.

Aging cell - 1 Jun 2009

Lee Sukkyoo, Van Remmen Holly, Csete Marie

Abstract excerpt

Mice lacking superoxide dismutase-2 (SOD2 or MnSOD) die during embryonic or early neonatal development, with diffuse superoxide-induced mitochondrial damage. Although stem and progenitor cells are exquisitely sensitive to oxidant stress, they have not been well studied in MnSOD2-manipulated mouse models. Patterns of proliferation and differentiation of cultured myoblasts (muscle progenitor cells), PI3-Akt...

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Source

Identifiers

PMID: 19627269
DOI: 10.1111/j.1474-9726.2009.00477.x

Genes

SOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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