Article
[Molecular mechanism of cell death induced by chemotherapeutic agents].
Brain and nerve = Shinkei kenkyu no shinpo - 1 Jul 2009
Saya Hideyuki
Abstract excerpt
Cells maintain their homeostasis by checkpoint mechanisms that exist at each phase of the cell cycle. Impairment of the checkpoint mechanisms induces DNA mutation and asymmetric segregation of chromosomes, which result in genomic instability, leading to malignant cell transformation. DNA-damaging...
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