Article
TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity.
Proceedings of the National Academy of Sciences of the United States of America - 28 Jul 2009
Kreslavsky Taras, Savage Adam K, Hobbs Robin, Gounari Fotini, Bronson Roderick, Pereira Pablo, Pandolfi Pier Paolo, Bendelac Albert, von Boehmer Harald
Abstract excerpt
Some gammadelta and alphabeta T lymphocytes exhibit an "innate" phenotype associated with rapid cytokine responses. The PLZF transcription factor is essential for the innate phenotype of NKT cells. This report shows that PLZF is likewise responsible for the innate, NKT-like phenotype of Vgamma1+V...
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