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Article

Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes.

Experimental cell research - 15 Oct 2009

Liovic Mirjana, D'Alessandro Mariella, Tomic-Canic Marjana, Bolshakov Viacheslav N, Coats Stephanie E, Lane E Birgitte

Abstract excerpt

The intermediate filament cytoskeleton is essential for the development and maintenance of normal tissue function. A number of diverse recent observations implicate these filament systems in sensing stress and protecting cells against its worst consequences. Cells expressing severely disruptive keratin mutations, characteristic of Dowling-Meara EBS, were previously reported to show elevated responses to...

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PMID: 19616543
DOI: 10.1016/j.yexcr.2009.07.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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